Table 2 QTLs for thalamus volume and brain gene expression

From: Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice

QTLs

Related gene

Phenotype

Correlation

P-value

Chr10 (D10Mit14)

2310043D08Rik

Brain weight

0.6405

0.004

  

Total hippocampus volume

0.5063

0.015

Chr11 (D11Mit19)

vamp2

Forebrain weight

0.5430

0.0053

  

Striatum volume

0.4419

0.0296

  

Morris water maze log latency 2

−0.4918

0.0439

 

4931428D14Rik

Brain weight

0.5840

0.0123

  

Stratum volume

0.4419

0.0296

  

Dopamine transporter expression in frontal cortex

0.6389

0.0324

  

Morris water maze log latency 2

−0.4918

0.0439

Chr16 (D16Mit100)

Fgd4

Volume of amygdala

−0.6904

6.85e-05

  

Hippocampus volume

−0.6858

0.00025

  

Forebrain weight

−0.5493

0.00466

  

Morris water maze site preference

0.8864

0.00496

  

Prepulse inhibition of the acoustic startle response

−0.6521

0.00498

  1. Selected genes located within thalamus volume QTLs. These genes were selected because their expression was significantly correlated with thalamus volume. Further, WebQTL analyses revealed that gene expression of the selected genes was also correlated with other measures of brain structure and/or behavioral performance.
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