Table 4 Predicted QTL effect: survival mean and standard deviation (days post-inoculation)

From: Biphasic survival analysis of trypanotolerance QTL in mice

Mortality phase

QTL genotype

MMU1

MMU5

MMU17

  

Mean

s.d.

Mean

s.d.

Mean

s.d.

Early

QQ

15.48

5.53

16.07

5.74

18.97

6.77

 

Qq

15.00

5.36

15.81

5.65

5.78

2.07

 

qq

14.35

5.12

14.94

5.34

5.33

1.90

Late

QQ

74.10

26.46

76.94

27.48

90.80

32.43

 

Qq

76.31

27.25

69.88

24.96

91.29

32.60

 

qq

51.90

18.53

49.71

17.75

55.28

19.74

Overall

QQ

71.28

28.73

73.05

30.50

76.00

41.09

 

Qq

72.35

30.39

67.29

26.98

86.43

37.34

 

qq

47.45

21.28

46.90

19.54

52.66

22.22

  1. Q=donor allele (C57BL/6), q=recipient allele (A/J). Results for early and late mortality phases were obtained by applying the estimated regression coefficients of the survival time submodels for each phase × QTL combination while specifying mean values for all other terms in the model, and using results for the mean and standard deviation of Weibull distributions.
  2. The overall results refer to the values for the mixture distribution (early and late phases), where the mixture probabilities were obtained from the estimated regression coefficients of the mortality phase model. See Appendix A for details of methods.
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