ABSTRACT
In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.
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10 May 2023
A Correction to this paper has been published: https://doi.org/10.1038/s41422-023-00805-3
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Acknowledgements
This work was supported by the Major State Basic Research Development program of China and the National High Technology Research and Development Program of China.
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SHI, Y., HE, L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Res 15, 97–98 (2005). https://doi.org/10.1038/sj.cr.7290272
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DOI: https://doi.org/10.1038/sj.cr.7290272
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