Figure 5
From: Scaffolded biosensors with designed DNA nanostructures

The tetrahedron-structured probe (TSP)-based biosensing platform for (a) DNA targets (adapted from Pei et al.58); (b) a small molecule, cocaine, with the split anticocaine aptamer (adapted from Wen et al.63); (c) a protein, thrombin, with a pair of antithrombin aptamers (adapted from Pei et al.58); and (d) immunological assays (adapted from Pei et al.66). HRP, horse radish peroxidase.