Figure 5
In vivo biocompatibility studies. (a) Representative microscope images (scale bar: 100 μm) of hematoxylin and eosin (H&E) stained tissue sections at 5 weeks post-implantation. (b) Evaluations of the histological score were performed in over 5 randomly chosen high-power fields in reference controls (HDPE) and test groups (means±s.e.m., n=5 per group). (c) Measured levels of inflammatory cytokines in peripheral blood serum by cytometric bead arrays (CBA). Statistical significance was determined by one-way analysis of variance (ANOVA) followed by Bonferroni’s multiple comparison test. Significance was ascribed at P<0.05. AdTi, adipose tissue; HDPE, high-density polyethylene; IFN-γ, interferon-γ; IL-10, interleukin-10; PMN, polymorphonuclear; SkMu, skeletal muscle; TNF-α, tumor necrosis factor.
