Figure 2 | NPG Asia Materials

Figure 2

From: Bio-inspired micropatterned hydrogel to direct and deconstruct hierarchical processing of geometry-force signals by human mesenchymal stem cells during smooth muscle cell differentiation

Figure 2

hMSC cell shape governs the spatial distribution and orientation of the SFs. The composite images, consisting of the filamentous actin network (gray scale) superimposed with the hue–saturation–brightness (HSB) color-coded map of the SFs orientation for the (a) circle, (b) AR 1:1, (c) AR 5:1, (d) AR 10:1 and (e) AR 15:1 shaped cells in relation to the x axis. Scale bar=15 μm. (f–j) Corresponding average circular histograms of the local SF orientation for the micropatterned cells. Numerical values denote the mean orientation angle of SFs from 15 individually patterned cells from each experimental group.

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