Figure 4 | NPG Asia Materials

Figure 4

From: An advanced in situ imaging method using heavy metal-doped hollow tubes to evaluate the biokinetics of carbon nanotubes in vivo

Figure 4

Magnetic resonance imaging (MRI) and macroscopic evaluation after tail vein injection of Gd-peapods. (a) The contrast-to-noise ratio (CNR) after injection. The CNR value in lungs increases with peapod concentration. However, individual samples do not show a significant time-dependence. The CNR values in livers, spleens, or kidneys from rats injected with Gd-peapods do not increase. (b) A matrix showing color changes in lungs. Time after the injection (vertical) versus peapod concentration (horizontal). Even after 3 weeks, lungs injected with pristine carbon nanotubes (CNTs) and Gd-peapods remain black. (c) CNR value in lungs change with peapod concentration change. The highest Gd-peapod concentration (250 μg) results in significant increase in CNR, in contrast to the control, pristine CNTs and Gd-peapods (25 μg; *P<0.05).

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