Figure 7

(a) Viability of A-253 tumor cell cells exposed to the test formulations measured with an MTT (MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Cells grown on a culture plate were used as a control group. Statistical analyses were performed using one-way analysis of variance with Bonferroni’s multiple comparison test (*P<0.001 and **P<0.05). (b) Optical and fluorescent images showing the morphology of A-253 cells treated with PBS, free Cur alone, Cur-M alone and Cur-M-loaded CCH at days 1, 2 and 3. Scale bars: 20 μm (× 200 magnification).