Figure 6

(a) In vivo biodistribution of nGO@DOX-cPEG in PC3 tumor xenograft mice (circle represents tumor area). Contours (concentration distribution) extracted from individual organs with (b) free Cy5.5 and (c) nGO@Cy5.5-cPEG are shown. (d) In vivo photothermal imaging upon NIR laser irradiation on tumors of mice pretreated with saline or nGO@DOX-cPEG. cPEG, chitosan-polyethylene glycol; Cy5.5, cyanin 5.5; DOX, doxorubicin; nGO, nanodimensional graphene oxide; NIR, near-infrared.