Figure 2
From: Lipid nanoparticle-mediated efficient delivery of CRISPR/Cas9 for tumor therapy

High-resolution transmission electron microscopy (HR-TEM) and dynamic light scattering (DLS) analysis of the nanoparticles. HR-TEM image of chondroitin/protamine/Cas9-sgRNA plasmid DNA (a) and PLNP/DNA-a (b), DLS analysis of the PLNP/DNA-a and Lipo2000/DNA-a in serum-free Dulbecco’s modified Eagle’s medium (DMEM) (c), Opti-MEM reduced serum medium (d) and 10% fetal bovine serum (FBS) DMEM (e).