Table 1 Summary of peptide sequences and frequencies in the third to fifth rounds of in vivo phage display against MCF-7 tumorsa

From: Guiding nanomaterials to tumors for breast cancer precision medicine: from tumor-targeting small-molecule discovery to targeted nanodrug delivery

Peptide sequences

Count/frequency (%)

 

3rd Rnd (30 cln)

4th Rnd (54 cln)

5th Rnd (162 cln)

Sum (246 cln)

AREYGTRFSLIGGYR

1/3.33

3/5.56

7/4.32

11/4.30

PKAFQYGGRAVGGLW

0

3/5.56

7/4.32

10/4.07

PVRYGFSGPRLAELW

0

0

3/1.85

3/1.22

RNVPPIFKEVYWIAQ

0

0

3/1.85

3/1.22

RTLIRMGTGAHAFAV

0

0

3/1.85

3/1.22

DRYLPINGVSMFGVP

0

0

2/1.23

2/0.81

IPVQFSTIDFVAASY

0

0

2/1.23

2/0.81

PGHSLGKLSVLHSFF

0

0

2/1.23

2/0.81

QADGPNSVVRPFTLT

0

0

2/1.23

2/0.81

RSFAYAAAPTSFPWV

0

0

2/1.23

2/0.81

SVGCPVVGTVGYLRCG

0

0

2/1.23

2/0.81

VRMFDYGVPRRAVYGG

0

0

2/1.23

2/0.81

  1. Abbreviations: cln, total phage colonies; Rd, round of biopanning.
  2. aOnly peptides with total colonies no <2 are included in this table.