Figure 5 | Acta Pharmacologica Sinica

Figure 5

From: Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12

Figure 5Figure 5

Confocal microscopy and line-scan profiles of fluorescence intensity of galectin-3 in PC-3 cells under 4 h stimulation of 100 μmol/L free KLA peptide. PC-3 cells were costained with green staining of (A) blank control, (B) Mito tracker, (C) ER tracker, (D) Gogli tracker, anti-galectin-3 antibody/FITC-conjugated secondray antibody (green staining) and DAPI (blue staining). Yellow spots in pictures denote the co-localization of the galectin-3 within mitochondrial compartments. The blue, green and red curve in the line-scan profiles represents the fluorescence intensity from DAPI, FITC and organelle-tracker Red respectively. White indicates the colocalization of organelle (red) and galectin-3 (green) analyzed using ImageJ software.

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