Figure 7 | Acta Pharmacologica Sinica

Figure 7

From: Two birds, one stone: dual targeting of the cancer cell surface and subcellular mitochondria by the galectin-3-binding peptide G3-C12

Figure 7Figure 7

Cell cytotoxicity and proapoptosis effect of KLA peptide and KLA-loaded HPMA copolymers. (A) Biocompatibility investigation of drug-free carrier HPMA copolymer and G3-C12-HPMA copolymer. (B) Viability of PC-3 cells treated with predetermined concentration of free KLA, HPMA-KLA and G3-C12-HPMA-KLA, respectively. (C) Apoptosis assay of PC-3 cells after treatments as indicated for 24 h at the equivalent KLA concentration of 25 nmol/mL.

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