Figure 3
From: Pterostilbene suppresses human endometrial cancer cells in vitro by down-regulating miR-663b
The miR-663b/BCL2L14 pathway plays an important role in PT effects in EC. (A) For the miR-663b mimic and siRNA-BCL2L14 groups, the cell proliferation of HTB-111 and Ishikawa cells was significantly higher than that of the NC group. (B) Data show that the miR-663b mimic and siRNA-BCL2L14 reduces the caspase activity induced by PT compared with the NC group (P<0.05). (C) The apoptosis ratio showed the same tendency as the caspase activity. The miR-663b mimic and siRNA-BCL2L14 mediated decreased apoptosis in the two EC cell lines.
