Figure 4 | Blood Cancer Journal

Figure 4

From: Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells

Figure 4

In vivo binding of HoxA9, Meis1 and Pbx1/2 at the c-myb promoter and first intron. X-ChIP experiments were performed on chromatin obtained from both HPC7 and FMH9 cells, and using antibodies directed against HoxA9, Meis1, Pbx1 or Pbx2. Purified immunoprecipitated DNA was used as a template for q-PCR amplifications and relative enrichments were measured against the control IgG ChIP material. The histograms represent the levels of enrichment at locations relative to the c-myb ATG and the width of the bars reflect the length of the PCR amplicons. Results are representative of three independent experiments.

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