Figure 6

Inhibition of MerTK significantly improves survival and delays disease progression in a Jurkat induced xenograft model of human leukemia. (a) Kaplan−Meier survival curves derived from NOD scid gamma mice mice injected with Jurkat parental or shRNA derivative cell lines. (b) Luciferase imaging of leukemia progression in NOD scid gamma mice mice injected with luciferase-tagged Jurkat and shRNA derivative cell lines and luciferin.