Table 4 Advanced anaplastic large cell lymphoma in children

From: Pediatric T- and NK-cell lymphomas: new biologic insights and treatment strategies

 

BFM 89

POG 92

SFOP 91

St Jude 90

MSKCC 107

CCG 93

BFM, SFOP, and UKCCSG 86

EICNHL 98

Patients (N)

89

67

82

18

19

86

225

352

Protocol(s)

NHL-BFM-90

POG 9315

HM89–91

CHOP-based

LSA2L2, LSA4

CCG-5941

BFM-86 and 90, SFOP HM89 and 91, and UKCCSG 9001-3

Modified NHL-BFM-90

Duration (months)

2–5

12

7–8

6–18

14–36

12

2–8

4–12

EFS (Est) 2–5 years

76%

73%

66%

57%

56%

68%

69%

75%

OS 2–5 years

NR

93%

83%

84%

84%

80%

81%

94%

  1. Abbreviations: BFM, Berlin–Frankfurt–Munster; CCG, Children's Cancer Group; EICNHL, European Intergroup for Childhood NHL; EFS, event-free survival; Est, estimate; MSKCC, Memorial Sloan Kettering Cancer Center; NHL, non-Hodgkin lymphoma; OS, overall survival; POG, Pediatric Oncology Group; SFOP, French Pediatric Oncology Group; UKCCSG, United Kingdom Children's Cancer Study Group.
  2. Adapted from Cairo.5
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