Figure 3

Molecular effects of nelfinavir on the UPR of myeloma cells. Myeloma cell samples from Figure 2a treated with either nelfinavir (N), ritonavir (R), saquinavir (S) or lopinavir (L) were assessed for expression of BIP, CHOP, p-IRE1α, Akt, p-AKT, p27 and polyubiquitinated protein by western blot.