Table 1 Identification of TCRs for the most relevant MAGE-C2/CT10-specific T-cell clones
TCC no. | TRBV | TRBJ | TRBD | CDR3 beta | TRAV | TRAJ | CDR3 alpha | MAGE-C2 peptide specificity |
|---|---|---|---|---|---|---|---|---|
3 | 7-3*01 | 2-3*01 | 2*02 | CASSLTGSAPTDTQYF | 8-1*01 | 37*01 | CAVKVNNAGNMLTF | 311–330 |
10 | 6-1*01 | 2-4*01 | 1*01 | CASSEHGQGVPAKNIQYF | 8-1*01 | 43*01 | CAVNARNNNDMRF | 171–190 |
20 | 7-8*01 | 1-6*01 | 1*01 | CASSLDLDRGNSPLHF | 2*01 | 29*01 | CAVEAYSGNTPLVF | 171–190 |
24 | 2*01 | 2-7*01 | 1*01 | CASSLGGQLREQYF | 26-1*01 | 47*01 | CIVRGLREYGNKLVF | 291–310 |
33 | 5-1*01 | 1-2*01 | 1*01 | CASSLALKAEDGYTF | 3*01 | 9*01 | CAVRDPHTGGFKTIF | 241–260 |
35 | 7-7*01 | 2-7*01 | 2*01 | CASSQNKVGEQYF | 12-2*02 | 8*01 | CAVNEDFQKLVF | 261–280 |
