Figure 4

Expression of PRDM1α mRNA in BL and LCL cell lines. PRDM1α mRNA levels in eight BL cell lines (six EBV-positive) and five LCLs were measured by real-time RT-PCR. Values are relative to the mRNA level in the myeloma cell line U266 (set as 100). BL cell lines that showed hypermethylation at the 5′ region are indicated. BCL6 status in these cell lines was determined by immunohistochemistry (data not shown).