Figure 1 | Blood Cancer Journal

Figure 1

From: Karyotype complexity and prognosis in acute myeloid leukemia

Figure 1

The flowcharts depicts all patients characterized by 3 (a) and 4 unrelated abnormalities (b), respectively, and end with the groups CK3 and CK4. Patients with (i) pure hyperdiploid karyotype (HDK), (ii) adverse-risk aberrations and (iii) t(9;11) were removed constituting distinct groups because of their strong specific influence on outcome per se. All of the complex aberrant patients with adverse abnormalities per se are summarized to the CK+adv group (n=333) resulting from n=35 CK3+adv and n=298 CK4+adv patients. CK3+adv consists of complex aberrant karyotypes with three unrelated aberrations with at least one specific adverse-risk aberration, without HDK, without t(9;11) and CK4+adv consists of complex karyotypes with 4 unrelated aberrations with at least one specific adverse-risk aberration, without HDK, without t(9;11).

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