Table 1 Identification of differentially expressed proteins

From: Histologically transformed follicular lymphoma exhibits protein profiles different from both non-transformed follicular and de novo diffuse large B-cell lymphoma

Fold change (ratio)	Identified protein	SwissProt database code	Number of identified peptides	Mascot score ^a	Molecular mass (Da)	Spot no. on 2D gels
Analysis A (FL^HT/FL^nonHT)
0.20	Glyceraldehyde-3-phosphate dehydrogenase	G3P_HUMAN	8	612	36201	8301
	Fructose-bisphosphate aldolase A	ALDOA_HUMAN	1	74	39851
0.25	NI					0505
0.26	Serum albumin fragment	ALBU_HUMAN	1	65	71317	3604
0.32	Vimentin fragment	VIME_HUMAN	9	480	53676	0501
0.41	ATP synthase subunit delta, mitochondrial	ATPD_HUMAN	2	133	17479	0006
	Myosin light polypeptide 6	MYL6_HUMAN	3	115	16919
3.23	Serum albumin fragment	ALBU_HUMAN	3	147	71317	3602
Analysis B (secondary DLBCL/ FL^HT)
0.28	NI					3005
0.31	Actin^b fragment	ACTB_HUMAN	5	456	42052	6003
0.40	Serine/arginine-rich splicing factor 2	SRSF2_HUMAN	1	100	25461	1305^c
0.45	HLA class I histocompatibility antigen, B-15 alpha chain	1B15_HUMAN	4	220	40648	3504
	Serpin B9	SPB9_HUMAN	9	498	43009
	Adenosine deaminase	ADA_HUMAN	3	121	41024
0.47	Serotransferrin	TRFE_HUMAN	1	68	79294	7901^d
0.49	NI					7001
3.67	Serine/arginine-rich splicing factor 1	SRSF1_HUMAN	2	74	27842	2309
2.37	Peroxiredoxin-1	PRDX1_HUMAN	2	79	22324	7104
2.21	Pyruvate kinase isozymes M1/M2	KPYM_HUMAN	21	1465	58470	8803^d,^e
	Catalase	CATA_HUMAN	2	126	59947
Analysis C (secondary DLBCL/de novo DLBCL)
0.26	Macrophage-capping protein fragment	CAPG_HUMAN	1	65	38760	3207^d
0.26	Coronin-1A	COR1A_HUMAN	6	388	51678	5802
0.31	Tubulin^b fragment	TBA1_HUMAN	4	306	50820	5401
	Alpha-enolase fragment	ENOA_HUMAN	2	97	47481
0.33	Actin^b	ACTA_HUMAN	1	77	42367	2409^c
0.33	Tubulin fragment	TBA1B_HUMAN	3	239	50804	2403^e
0.36	Cofilin-1 fragment	COF1_HUMAN	1	75	18719	3003
0.37	Serum albumin fragment	ALBU_HUMAN	2	93	71317	5202
0.42	Serum albumin fragment	ALBU_HUMAN	5	316	71317	3603^e
0.45	Heterogeneous nuclear ribonucleoprotein H fragment	HNRH1_HUMAN	4	276	49484	6202
0.45	HLA class I histocompatibility antigen^b	1A02_HUMAN	3	114	41181	5507
	HLA class I histocompatibility antigen^b	1B15_HUMAN	2	112	40648
0.45	Pyruvate kinase isozymes M1/M2 fragment	KPYM_HUMAN	6	251	58522	6408
0.45	Serotransferrin	TRFE_HUMAN	1	68	79294	7901^d
0.46	NI					7001^d
0.46	NI					4002
0.46	Glyceraldehyde-3-phosphate dehydrogenase	G3P_HUMAN	4	292	36201	7305
0.47	Tubulin^b fragment	TBB5_HUMAN	6	324	50095	4403
0.48	Actin^b	ACTB_HUMAN	6	523	42052	3405
	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	ODPB_HUMAN	2	140	39550
3.45	NI					4910
3.33	Gelsolin	GELS_HUMAN	2	72	86043	4911
3.13	Brain acid soluble protein 1	BASP1_HUMAN	4	163	22680	0610
2.70	Glyceraldehyde-3-phosphate dehydrogenase	G3P_HUMAN	7	584	36201	8403
	Glyceraldehyde-3-phosphate dehydrogenase	G3P_NEUCR	1	52	36384
	Malate dehydrogenase, mitochondrial	MDHM_HUMAN	7	370	35937
	Annexin A2	ANXA2_HUMAN	1	56	38873
2.50	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta	GBB1_HUMAN	3	182	38151	3407^e
2.44	Pyruvate kinase isozymes M1/M2	KPYM_HUMAN	20	1374	58470	8805^e
	Catalase	CATA_HUMAN	1	48	59947
2.38	Vimentin	VIME_HUMAN	9	446	53676	1710
	Tubulin^b	TBA1B_HUMAN	4	204	50804
2.33	Serum albumin	ALBU_HUMAN	16	1030	71317	4906
2.33	Pyruvate kinase isozymes M1/M2	KPYM_HUMAN	21	1465	58470	8803^d,^e
	Catalase	CATA_HUMAN	2	126	59947
2.17	Perilipin-3	PLIN3_HUMAN	2	240	47046	1606
2.04	Proteasome subunit beta type-9	PSB9_HUMAN	4	260	23364	0103

Abrreviations: DLBC, diffuse large B-cell lymphoma; 2D, two-dimensional; FL, follicular lymphoma; HT, histological transformation; no., number; NI, Not identified.
^aMascot score: Ion score is −10*Log(P), where P is the probability that the observed match is a random event.
^bA number of variants was found. Top hit listed.
^cContaminated with tubulin from previous samples.
^dIdentified from analysis B as well as analysis C.
^eFew additional significant peptides were found with scores just above significance level.

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Table 1 Identification of differentially expressed proteins

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