Figure 4 | Blood Cancer Journal

Figure 4

From: PD-1hiTIM-3+ T cells associate with and predict leukemia relapse in AML patients post allogeneic stem cell transplantation

Figure 4

PD-1hiTIM3+ cells produce less cytokines in response to anti-CD3/anti-CD28 stimulation. Production of TNF-α, IFN-γ and IL-2 upon in vitro anti-CD3/anti-CD28 stimulation. Shown is cytokine release from CD4+ (a) or CD8+ (b) T cells gated on each fraction of cells based on PD-1 and TIM-3 expression. Representative plots from a single relapse patient (09) are shown.

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