Table 2 Cytogenetic/molecular risk and treatment outcome of 41 patients with AML, stratified by Twist1 expression level

From: Favorable clinical outcome and unique characteristics in association with Twist1 overexpression in de novo acute myeloid leukemia

 

Twist1 (+)

Twist1 (−)

P-value

Cytogenetic risk

  

0.222

 Good

2

0

 

 Intermediate

15

16

 

 Poor

1

3

 

NPM1 mutation

  

0.464

 Mutated

7

3

 

 Wild type

15

15

 

FLT3 mutation

  

1.000

 Mutated

5

4

 

 Wild type

17

14

 

Molecular/cytogenetic risk

  

0.031

 Good

5

0

 

 Intermediate

15

13

 

 Poor

2

6

 

Achievement of CR

  

0.013

 Yes

13

6

 

 No

1

7

 

No. of chemo cycles to CR

1.1±0.3

1.8±1.2

0.037

  1. Abbreviations: AML, acute myeloid leukemia; CR, complete remission. P-values with statistically significant differences are shown in bold.
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