Figure 6 | Blood Cancer Journal

Figure 6

From: Bispecific antibody releasing-mesenchymal stromal cell machinery for retargeting T cells towards acute myeloid leukemia blasts

Figure 6

BsAb-releasing hMSCs prevent the establishment of AML in NOD/SCID IL2Rγ−/− (NSG) mice. Kaplan–Meier survival analysis of NSG mice after intravenous injection of T cells and MOLM-13 AML cells at an e:t ratio of 5:1 together with vector control containing (dashed line) or bsAb-releasing (black line) hMSCs, indicated as control (n=5) and treatment group (n=4), respectively. A log-rank test was performed to determine the statistical significance in survival between the groups from ongoing experiment. **P<0.01.

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