Table 1 Multivariable Cox proportional hazard regression analysis in 301 patients with primary myelofibrosis

From: Bone marrow fibrosis grade is an independent risk factor for overall survival in patients with primary myelofibrosis

Variable

HR

95% CI

P

Score

DIPSS intermediate-2-risk group

2.31

1.43–3.73

0.001

1

DIPSS high-risk group

6.17

2.50–15.23

<0001

2

Platelets <100 Ă— 109/l

2.65

1.62–4.34

<0.001

1

No palpable splenomegaly

1.72

1.03–2.86

0.036

0.5

CALR-type-2 or triple-negative mutation

1.82

1.10–3.02

0.02

0.5

Fibrosis grade 2 or 3

2.51

1.37–4.59

0.003

1

  1. Abbreviations: CI, confidence interval; DIPSS, Dynamic International Prognostic Scoring System; HR, hazard ratio.
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