Table 1 Patient characteristics (n=14)

From: Comparison of intramedullary myeloma and corresponding extramedullary soft tissue plasmacytomas using genetic mutational panel analyses

Patient no

Gender

Age at diagnosis

Ig-type

% PC in diagnostic BM

Lines of therapy before EM

EM years after diagnosis

Cytogenetics

Allogeneic SCT

1

F

46

IgGλ

60%

5

7

48 XX

FISH:nd

Yes

2

F

49

IgGκ

40%

10

11

56 XX (hyperdiploid)

FISH: no deletions

Yes

3

M

35

Light chain

35%

2

1

FISH: 1q+

No

4

F

63

Light chain

ND

2

1

FISH: 1q+

Yes

5

M

30

IgGκ

NA

0

0

ND

No

6

M

61

IgAλ

90%

2

0.5

ND

No

7

M

49

IgGκ

40%

7

5

Hyperdiploid

FISH: 1q+

Yes

8

F

69

IgGκ

70%

2

2

46 XX

Fish del 13q14, trisomy 9

No

9

M

64

Light chain

90%

1

1

46 XY

FISH: no deletions

No

10

M

52

IgAκ

NA

5

4

ND

Yes

11

M

69

IgGλ

NA

2

1

ND

No

12

M

43

IgGκ

NA

9

10

56-56 XY (hyperdiploid)

FISH: no deletions

Yes

13

M

55

IgGκ

85%

6

6

ND

Yes

14

F

39

IgGλ

40%

0

0

Near tetraploid

FISH: no deletions

No

  1. Abbreviations: EM, extramedullary; NA, not applicable; ND, not determined; PC, plasma cells; SCT, stem cell transplantation.