Table 1 Baseline patient characteristics (n=35)

From: A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia

Patient characteristic

Age, median (range)

56 (29–70)

Gender

 Male (%)

18 (51)

 Female (%)

17 (49)

ECOG performance status

 0 (%)

15 (43)

 1 (%)

15 (43)

 2 (%)

4 (11)

 Missing (%)

1 (3)

Onset of AML

 De novo (%)

23 (66)

 Therapy-related (%)

12 (34)

 Prior MDS/MPN (%)

4 (11)

Indication for treatment

 Primary refractory (%)

10 (29)

 First relapse (%)

21 (60)

 Second relapse (%)

4 (11)

Prior unsuccessful salvage chemotherapy (%)

7 (20)

Prior allogeneic HCT (%)

10 (29)

Cytogenetics

 Favorable (%)

3 (9)

 Intermediate (%)

19 (54)

 Poor (%)

13 (37)

WBC k/cumm (range)

2.5 (0.2–14.7)

BM blast % (range)

33 (0–96)

  1. Abbreviations: AML, acute myeloid leukemia; BM, bone marrow; ECOG, Eastern Cooperative Oncology Group; HCT, hematopoietic cell transplantation; MDS, myelodysplastic syndrome; MPN, myeloproliferative neoplasm; WBC, white blood cells.