Table 1 Prevalence of HBV and HCV infection in patients with different types of B-cell non-Hodgkin lymphoma

From: Prevalence of hepatitis B and hepatitis C viral infections in various subtypes of B-cell non-Hodgkin lymphoma: confirmation of the association with splenic marginal zone lymphoma

Category

Total (N)

HBs-Ag infection rate

Unadjusted odds ratio (95% CI)

P value

HCV infection rate

Unadjusted odds ratio (95% CI)

P value

  

N

%

  

N

%

  

General population

81 775

5888

7.2

Reference

     

General population

78 746

    

316

0.40

Reference

 

B-NHL patients

881

79

9.0

1.270 (1.006-1.602)

0.044

16

1.8

4.606 (2.775-7.645)

0.000

Indolent B-NHL

733

58

7.9

1.107 (0.846-1.450)

0.458

14

1.9

4.848 (2.824-8.322)

0.000

Aggressive B-NHL

148

21

14.2

2.131 (1.342-3.384)

0.001

2

1.35

3.411 (0.841-13.828)

0.068

According to indolent lymphoma subtype

 SMZL

48

9

18.8

2.974 (1.440-6.143)

0.002

2

4.2

10.826 (2.617-44.788)

0.000

 CLL

279

21

7.5

1.049 (0.672-1.638)

0.833

6

2.2

5.472 (2.419-12.380)

0.000

 LPL/WM

119

6

5.1

0.684 (0.301-1.556)

0.363

3

2.6

6.439 (2.036-20.366)

0.000

 FL

74

6

8.1

1.137 (0.493-2.621)

0.763

0

0

 

0.586

 B-LPDu

132

10

7.5

1.056 (0.554-2.014)

0.868

1

0.76

1.901 (0.265-13.636)

0.516

 HCL

33

4

12.5

1.778 (0.625-5.058)

0.274

1

3.0

7.781 (1.060-57.116)

0.017

 NMZL

27

3

11.1

1.611 (0.485-5.352)

0.432

1

3.7

9.576 (1.296-70.786)

0.007

 MALT

15

0

0

 

0.281

0

0

 

0.806

 B-PLL

6

0

0

 

0.495

0

0

 

0.877

According to aggressive lymphoma subtype

 DLBCL

58

12

20.7

3.362 (1.780-6.350)

0.000

0

0

 

0.629

 MCL

59

8

13.6

2.022 (0.959-4.262)

0.059

2

3.5

9.054 (2.199-37.279)

0.000

 Burkitt lymphoma

2

0

0

 

0.694

0

0

 

0.929

 B-LBL

14

0

0

 

0.297

0

0

 

0.813

 Aggressive B-NHL unclassified

15

1

6.7

0.921 (0.121-7.002)

0.936

0

0

 

0.806

  1. Abbreviations: B-LBL, B-cell lymphoblastic lymphoma; B-LPDu, unclassified B-cell chronic lymphoproliferative disorders; B-NHL, B-cell non-Hodgkin Lymphoma; B-PLL, B-cell prolymphocytic leukemia; CLL, chronic lymphocytic leukemia; DLBCL, diffuse large B-cell lymphoma; HBV, hepatitis B virus; HCL, hairy cell leukemia; HCV, hepatitis C virus; FL, follicular lymphoma; LPL/WM, lymphoplasmacytic lymphoma/Waldenström macroglobulinemia; MALT, mucosa-associated lymphoma; MCL, mantle cell lymphoma; NMZL, nodal marginal zone lymphoma; SMZL, splenic marginal zone lymphoma. P value comes from comparison with general population; bold indicates significant difference (P<0.05).
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