Figure 1

Simon–Makuch plot of overall survival (OS) according to the achievement of (a) any IWG-2006 defined response, (b) any overlap-MDS/MPN defined response and (c) type of overlap-MDS/MPN defined response: complete response (CR), optimal marrow response (OMR), clinical Benefit (CB) and partial marrow response (PMR), and lack of response (Stable disease (SD) or progressive disease (PD)). Achievement of response was considered as a time-dependent variable and OS is censored at the date of last follow-up or allogeneic transplantation.