Figure 4 | Blood Cancer Journal

Figure 4

From: The thrombopoietin/MPL axis is activated in the Gata1low mouse model of myelofibrosis and is associated with a defective RPS14 signature

Figure 4

Rux decreases the TGF-β content of the bone marrow and the spleen from Gata1low mice. (a) Representative immunostaining with TGF-β antibodies of bone marrow (BM) and spleen sections from Gata1low mice treated with either vehicle or Rux, as indicated. Magnification × 40. (b) Computer-assisted quantification of the intensity of TGF-β immunostaining of bone marrow and spleen sections of the groups presented in a. Results are presented as mean (±s.d.) of those obtained by evaluating three to four sections per mouse, three mice per group. P-values were calculated by analysis of variance.

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