Figure 2 | Blood Cancer Journal

Figure 2

From: Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies

Figure 2

IgG1 anti-CD47 mAbs mediate ADCP and ADCC activity. ADCP of HL60 (a), Kasumi-3 (b), or MV4-11 (c) cells by human PBMC-derived macrophages in response to IgG1/IgG2σ anti-CD47 mAbs. (d) ADCC of human PBMC against HL60 target cells in response to increasing concentrations of IgG1 anti-CD47 mAbs. (e) CDC against WIL2-S target cells in the presence of human complement in response to increasing concentrations of IgG1 anti-CD47 mAbs.

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