Figure 5
From: Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies
Non-human primate study with IgG1 and IgG2σ C47B222-(CHO). (a) Non-naive female cynomolgus monkeys were treated with anti-CD47 mAbs as detailed in schematic (n=4/group). Graphs summarize changes in red blood cell (b), hematocrit (c), hemoglobin (d), and reticulocyte levels (e) in response to treatment with IgG1 and IgG2σ C47B222-(CHO). Arrows above graphs indicate dosing with mAbs.
