Table 1 Anti-CD47 mAb characteristics
From: Anti-leukemic activity and tolerability of anti-human CD47 monoclonal antibodies
Ab ID | Human CD47 K D | Cyno CD47 K D | K D ratio | SIRPα-blocking |
|---|---|---|---|---|
(n M) | (n M) | Cyno/Human | EC 50 (μg/ml) | |
C47B157 | 3.53 | 3.71 | 1.1 | 0.13 |
C47B161 | 2.87 | 2.96 | 1.0 | 0.06 |
C47B222 | 1.12 | 0.84 | 0.8 | 0.04 |
