Table 2 Change from baseline to weeks 8, 16 and 24 for Schiff sensitivity score and tactile threshold (intent-to-treat population)

From: Clinical study to monitor dentinal hypersensitivity with episodic use of a desensitising dentifrice

 

Episodic use (n=38)

Continuous use (n=38)

Continuous versus episodic use

Schiff sensitivity score

 Baseline mean (s.e.)

2.37 (0.07)

2.42 (0.08)

 

Change from baseline, adjusted mean (95% CI)

Difference (95% CI), P-value a

 Week 8

−0.36 (−0.52, −0.21)*

−0.26 (−0.42, −0.11)*

0.1 (−0.12, 0.32), 0.358

 Week 16

−0.24 (−0.39, −0.09)*

−0.39 (−0.55, −0.24)*

−0.15 (−0.37, 0.07), 0.170

 Week 24

−0.48 (−0.67, −0.29)*

−0.47 (−0.66, −0.29)*

0.01 (−0.25, 0.27), 0.941

Tactile threshold (g)

 Baseline mean (s.e.) (median)

10.92 (0.370) (10.00)

10.92 (0.370) (10.00)

 

Change from baseline, mean (±s.e.) (median)

Difference (95% CI), P-value b

 Week 8

0.71 (0.965) (0.00)

2.57 (2.313) (0.00)

0 (0.00, 0.00), 0.857

 Week 16

2.65 (2.103) (0.00)

8.38 (3.382) (0.00)

0 (0.00, 0.00), 0.253

 Week 24

8.48 (3.485) (0.00)

5.59 (2.791) (0.00)

0 (0.00, 0.00), 0.563

  1. Abbreviations: CI, confidence interval; s.e., standard error.
  2. aANCOVA with fixed effects for treatment, visit and treatment-by-visit interaction; baseline Schiff score as covariate.
  3. b CI for median difference based on Hodges–Lehmann method, P-value based on Wilcoxon rank-sum test.
  4. *P<0.05, t test.