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The Induction of Adenomata in Mouse Lung Homografts by Chemical Carcinogens

Abstract

Implants of lung from 18-day-old embryo BALB/c mice of an inbred strain were exposed to 3,4-benz(a)pyrene or 1,2,5,6-dibenzanthracene and introduced subcutaneously into 6-week-old mice of the same strain. Lung adenomata developed within 16 weeks.

There was no evidence of an effect of either chemical carcinogen on the subcutaneous tissue of the host animal.

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Davies, R., Major, I. & Aberdeen, E. The Induction of Adenomata in Mouse Lung Homografts by Chemical Carcinogens. Br J Cancer 25, 565–567 (1971). https://doi.org/10.1038/bjc.1971.71

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  • DOI: https://doi.org/10.1038/bjc.1971.71

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