Abstract
A significant correlation (r = -0.48) was found between the logarithm of the S-phase fraction of the primary tumour (SPF) and the logarithm of the doubling time of lung metastases (T2). The estimated median cell loss factor was 88% (range 35-99%).
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Blomqvist, C., Huuhtanen, R., Pan, Y. et al. Growth rate of lung metastases and S-phase fraction as determined by flow cytometry from the primary tumour in 25 patients with bone or soft-tissue sarcomas. Br J Cancer 73, 1556–1559 (1996). https://doi.org/10.1038/bjc.1996.293
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DOI: https://doi.org/10.1038/bjc.1996.293