Table 1 Comparison of clinicopathological factors between patients with high and low c-Met expression in IHCC

From: Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma

 

c-Met

 
 

High

Low

P -value

Gender

 Male

7

59

0.7636

 Female

6

39

 

Age

 ⩾65

9

48

0.2396

 < 65

4

50

 

Tumour size

 ⩾5 cm

8

39

0.2430

 <5 cm

5

52

 

Macroscopic type

 Mass forming

10

83

0.4397

 Non-mass forming

3

15

 

Intrahepatic metastasis

 Negative

8

70

0.5229

 Positive

5

28

 

Invasion to hepatic vein

 Negative

5

53

0.2496

 Positive

8

41

 

Invasion to portal vein

 Negative

1

24

0.2907

 Positive

12

73

 

Lymph node metastasis

   

 Negative

7

57

0.7739

 Positive

6

41

 

Histopathological classification

 Well differentiated

4

21

0.5943

 Moderately differentiated

8

73

 

 Poorly differentiated

1

4

 

UICC pT

 In situ+1+2a+2b

4

28

>0.9999

 3+4

9

70

 

UICC stage

 I+II

8

51

0.5680

 III+IVA

5

47

 

Lymphatic vessel invasion

 Negative

2

37

>0.9999

 Positive

11

61

 

Venous invasion

 Negative

1

19

0.4566

 Positive

12

79

 

Perineural invasion

 Negative

4

27

0.7536

 Positive

9

71

 

Hepatic surgical margin

 Negative

9

84

0.2202

 Positive

4

14

 

Bile duct margin

 Negative

10

86

0.3797

 Positive

3

12

 

EGFR expression

 Negative

5

72

0.0063

 Positive

8

21

 

VEGF expression

 Negative

7

51

0.5697

 Positive

6

42

 

HER2 expression

 Negative

13

92

>0.9999

 Positive

0

1

 
  1. Abbreviations: EGFR=epidermal growth factor receptor; IHCC=intrahepatic CC; UICC=Union for International Cancer Control; VEGF=vascular epithelial growth factor.