Table 4 Combined effect of dietary folate intake and alcohol consumption on breast cancer risk

From: Low-to-moderate alcohol intake and breast cancer risk in Chinese women

Ethanol intake (g per day)

Folate intake ( μ g per day)

No. Cases/ controls

OR (95% CI) a

P- value b

Abstainers

Low

245/177

1.00b

 
 

Middle

229/166

0.70 (0.51–0.95)

 
 

High

186/186

0.30 (0.20–0.44)

 

>0–<15

Low

70/136

0.43 (0.30–0.61)

<0.001

 

Middle

99/154

0.35 (0.25–0.50)

 
 

High

87/122

0.23 (0.15–0.36)

 

15

Low

21/18

0.93 (0.47–1.84)

 
 

Middle

21/12

0.99 (0.46–2.16)

 
 

High

36/28

0.38 (0.20–0.72)

 
  1. Abbreviations: CI=confidence interval; OR=odds ratio.
  2. aEstimates from unconditional logistic regression models included terms for age at interview (continuous), education (none, primary, secondary, tertiary), BMI (5-years ago), oral contraceptive use (never, ever), hormone replacement therapy (never, ever), breast cancer in first-degree relatives (no, yes), total energy intake (continuous), folate intake (continuous), tea drinking (no, yes) and menopausal status (no, yes; only for all women).
  3. bReference category.