Table 1 Known prostate cancer risk SNPs successfully tested in this study

From: Genetic architecture of prostate cancer in the Ashkenazi Jewish population

SNP

Chr.

Gene

Alleles (Maj/Min)

MAF

Prev. OR

Citation

rs721048

2

EHBP1

G/A

0.19

1.15

Gudmundsson et al (2008)

rs2660753

3

CHMP2B; POU1F1

C/T

0.11

1.18

Eeles et al (2008)

rs9364554

6

SLC22A3; SLC22A2; LPAL2; LPA

C/T

0.29

1.17

Eeles et al (2008)

rs10486567

7

JAZF1

G/A

0.23

0.74

Thomas et al (2008)

rs6465657

7

LMTK2; BHLHB8

T/C

0.46

1.12

Eeles et al (2008)

rs7008482

8

T/G

0.83

1.8

Robbins et al (2007)

rs1016343

8

C/T

0.18

1.37

Eeles et al (2008)

rs13254738

8

A/C

0.34

1.11

Haiman et al (2007)

rs16901979

8

C/A

0.031

1.79

Gudmundsson et al (2007a)

rs6983267

8

G/T

0.50

0.8

Yeager et al (2007)

rs7000448

8

C/T

0.39

1.14

Haiman et al (2007)

rs4242382

8

G/A

0.12

1.41

Thomas et al (2008)

rs4242384

8

A/C

0.09

1.88

Eeles et al (2008)

rs7920517

10

MSMB

G/A

0.48

0.82

Eeles et al (2008)

rs10993994

10

MSMB

T/C

0.60

0.8

Eeles et al (2008)

rs4962416

10

CTBP2

T/C

0.27

1.2

Thomas et al (2008)

rs7931342

11

G/T

0.49

0.84

Eeles et al (2008)

rs10896449

11

G/A

0.48

0.78

Thomas et al (2008)

rs4430796

17

TCF2

G/A

0.49

1.24

Gudmundsson et al (2007b)

rs7501939

17

TCF2

C/T

0.42

0.83

Gudmundsson et al (2007b)

rs1859962

17

G/T

0.54

0.8

Gudmundsson et al (2007b)

rs2735839

19

KLK2; KLK3

G/A

0.15

0.83

Eeles et al (2008)

rs5945572

X

NUDT11; NUDT10

G/A

0.35

1.24

Gudmundsson et al (2008)

  1. Abbreviations: alleles=major/minor alleles; chr.=chromosome; gene=nearby gene as reported in the cited literature; MAF=allele frequency in the controls of the cited paper for the minor allele as observed in the Ashkenazi Jewish population; prev. OR=previous odds ratio for the SNP as cited by the given paper; SNP=single nucleotide polymorphism.
  2. When MAF is >0.5, it indicates that the minor allele in the Ashkenazi Jewish population is the major allele in the study that initially reported the SNP.