Table 2 Genotype counts and deviation from Hardy–Weinberg equilibrium stratified by disease status and source study
From: Genetic architecture of prostate cancer in the Ashkenazi Jewish population
Genotype counts (Hardy–Weinberg P) | |||||||
|---|---|---|---|---|---|---|---|
SNP | Alleles (Maj/min) | MAF in controls | MSKCC controls | NLGIP controls | Israeli blood bank controls | MSKCC cases | Montreal cases |
rs721048 | G/A | 0.14 | 7/99/303 (1) | 2/46/112 (0.37) | 30/299/912 (0.36) | 21/214/575 (0.79) | 2/11/51 (0.19) |
rs2660753 | C/T | 0.24 | 27/156/226 (1) | 14/50/95 (0.084) | 69/445/727 (0.94) | 57/297/456 (0.35) | 1/21/42 (0.67) |
rs9364554 | C/T | 0.19 | 10/117/282 (0.72) | 10/55/95 (0.66) | 51/386/804 (0.59) | 32/272/506 (0.59) | 5/19/40 (0.28) |
rs10486567 | G/A | 0.29 | 42/143/224 (0.013) | 12/57/91 (0.53) | 112/513/614 (0.73) | 60/342/408 (0.34) | 5/24/34 (0.75) |
rs6465657 | T/C | 0.41 | 77/188/142 (0.31) | 34/82/44 (0.75) | 200/578/459 (0.44) | 165/386/259 (0.35) | 13/27/24 (0.31) |
rs7008482 | T/G | 0.38 | 68/179/160 (0.14) | 22/64/71 (0.22) | 175/598/464 (0.47) | 104/339/346 (0.16) | 5/21/38 (0.49) |
rs1016343 | C/T | 0.19 | 10/130/269 (0.25) | 6/47/107 (0.79) | 48/372/819 (0.46) | 38/282/489 (0.84) | 3/23/38 (1) |
rs13254738 | A/C | 0.41 | 64/204/141 (0.54) | 29/70/61 (0.25) | 218/572/447 (0.14) | 153/425/232 (0.10) | 9/34/21 (0.60) |
rs16901979 | C/A | 0.04 | 1/34/374 (0.55) | 0/10/147 (1) | ND | 1/62/748 (1) | 0/8/55 (1) |
rs6983267 | G/T | 0.50 | 96/207/104 (0.77) | 36/82/42 (0.87) | 318/615/305 (0.82) | 168/391/249 (0.52) | 12/27/25 (0.43) |
rs7000448 | C/T | 0.48 | 90/203/116 (1) | 39/85/36 (0.53) | 279/606/341 (0.77) | 234/380/191 (0.14) | 16/26/21 (0.21) |
rs4242382 | G/A | 0.065 | 1/62/345 (0.49) | 0/14/146 (1) | 4/150/1087 (0.81) | 8/125/677 (0.38) | 0/5/59 (1) |
rs4242384 | A/C | 0.062 | 1/57/351 (0.71) | 0/12/148 (1) | ND | 5/118/687 (1) | 0/5/59 (1) |
rs7920517 | G/A | 0.45 | 81/194/132 (0.55) | 42/75/41 (0.53) | 250/605/386 (0.65) | 150/392/268 (0.77) | 12/33/19 (0.80) |
rs10993994 | T/C | 0.50 | 97/202/109 (0.84) | 46/77/35 (0.87) | 305/634/301 (0.46) | 184/396/229 (0.62) | 13/34/17 (0.80) |
rs4962416 | T/C | 0.33 | 46/193/170 (0.51) | 18/78/64 (0.49) | 133/516/591 (0.21) | 95/344/370 (0.27) | 6/25/33 (0.76) |
rs7931342 | G/T | 0.33 | 46/173/185 (0.57) | 20/71/69 (0.86) | 149/533/556 (0.23) | 69/319/422 (0.44) | 6/29/29 (1) |
rs10896449 | G/A | 0.34 | 52/175/181 (0.38) | 20/72/68 (0.86) | 155/542/543 (0.28) | 76/321/411 (0.27) | 6/29/29 (1) |
rs4430796 | G/A | 0.43 | 69/206/134 (0.54) | 35/76/49 (0.63) | 225/607/392 (0.73) | 183/397/230 (0.67) | 11/35/18 (0.46) |
rs7501939 | C/T | 0.44 | 82/206/121 (0.77) | 29/77/52 (1) | 222/614/390 (0.49) | 131/395/283 (0.77) | 13/31/19 (1) |
rs1859962 | G/T | 0.47 | 99/189/121 (0.14) | 27/89/41 (0.11) | ND | 157/392/262 (0.67) | 14/36/14 (0.45) |
rs2735839 | G/A | 0.18 | 8/119/281 (0.37) | 8/42/110 (0.18) | 50/372/818 (0.36) | 30/210/570 (0.058) | 3/22/39 (1) |
rs5945572 | G/A | 0.25 | 97/5/307 (NA) | 47/2/110 (NA) | 303/0/936 (NA) | 244/2/563 (NA) | 17/0/47 (NA) |
