Figure 2
Representative sections of normal oral mucosa taken from patient biopsies (NOM) (A–E) and tissue-engineered normal oral mucosa constructs (TENOM) (F–J). TENOM models were generated by culturing normal oral keratinocytes and normal oral fibroblasts on DED at an air/liquid interface for 14 days. Sections have been stained with H&E (A and F) and immunohistochemically stained to show the pattern of expression of Ki67 (B and G), AE1/3 (C and H), collagen type IV (Col IV; D and I) and integrin αvβ6 (E and J) and counterstained with haematoxylin. Scale bar indicates 200 μm.
