Table 2 Targets of the 13-gene miRNA signature were annotated for pathway membership using Ingenuity Pathway Analysis (IPA)
MicroRNA (hsa-mir-x) | Top canonical pathway (IPA) | P -value of enrichment (IPA) |
|---|---|---|
140-3p | Glycophospholipid biosynthesis | 6.99E–02 |
628-5p | B-cell development | 1.02E–02 |
518f | Antiproliferative role of the somatostatin receptor 2 | 3.89E–02 |
636 | TGFβ signalling | 2.54E–03 |
301a | Wnt/β catenin | 1.99E–03 |
34c | Serotonin receptor signalling | 3.66E–02 |
224 | Hypoxia signalling | 1.19E–02 |
197 | Role of stromal cells in rheumatoid arthritis | 1.31E–02 |
205 | Biosynthesis of steroids | 1.89E–02 |
135b | Circadium rhythm | 2.6E–02 |
200b | Wnt/GSK signalling | 4E–03 |
200c | Wnt/β catenin | 8.17E–03 |
141 | Integrin signalling | 11.8E–04 |
