Figure 1 | British Journal of Cancer

Figure 1

From: Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancer

Figure 1

Prognostic performance of the specific activities of CDK1 and CDK2. (A) All cases (n=254) plotted on a scatter diagram with logarithmic scales according to CDK1SA and CDK2SA, respectively. Red symbols: patient with distant metastasis, black symbol: no metastasis. (B and C) Time-dependent ROC analysis against CDK1SA (B) or CDK2SA (C). Thick line: concordance index, thin line: 95% CI. Concordance index was 0.69 for CDK1SA (95% CI: 0.55–0.79, P=0.036), and 0.51 for CDK2SA (95% CI: 0.25–0.66, P=0.57). (D) Derivation of an optimal CDK1SA cutoff value. The maximum log-rank test statistic was obtained when CDK1SA was 11 or 18 (maU eU–1).

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