Table 2 Hazard ratios (HR) and 95% confidence intervals (95% CI) of death by categories of alcohol intake among 3146 invasive breast cancer cases in the Swedish Mammography Cohort

From: Alcohol intake and mortality among women with invasive breast cancer

 

Alcohol intake (g per day)

 
 

Non-drinker

<3.4

3.4–9.9

⩾10

P trend a

Median alcohol intake (g per day)

0

1.8

5.0

12.4

 

Person-years

7714

10 431

6515

1280

 

Breast cancer deaths

133

149

85

18

 

 Age-adjusted model

1.00

0.85 (0.68–1.08)

0.79 (0.60–1.05)

0.85 (0.51–1.39)

0.26

 Covariate-adjusted modelb

1.00

0.93 (0.73–1.18)

0.94 (0.70–1.25)

1.09 (0.66–1.81)

0.87

 Covariate-adjusted model+clinical characteristicsc

1.00

0.95 (0.74–1.21)

0.94 (0.70–1.25)

1.36 (0.82–2.26)

0.47

Non-breast cancer deaths

224

172

66

13

 

 Age-adjusted model

1.00

0.74 (0.61–0.91)

0.65 (0.49–0.85)

0.77 (0.44–1.35)

0.01

 Covariate-adjusted modelb

1.00

0.76 (0.62–0.93)

0.66 (0.50–0.89)

0.79 (0.45–1.29)

0.03

 Covariate-adjusted model+clinical characteristicsc

1.00

0.77 (0.73–0.95)

0.67 (0.50–0.90)

0.81 (0.46–1.43)

0.04

Total deaths

357

321

151

31

 

 Age-adjusted model

1.00

0.79 (0.68–0.92)

0.71 (0.59–0.87)

0.80 (0.56–1.16)

0.01

 Covariate-adjusted modelb

1.00

0.83 (0.71–0.97)

0.79 (0.64–0.96)

0.92 (0.63–1.34)

0.16

 Covariate-adjusted model+clinical characteristicsc

1.00

0.85 (0.73–1.00)

0.80 (0.65–0.98)

1.03 (0.71–1.51)

0.36

  1. aDetermined using category medians.
  2. bCox proportional hazard model adjusted for age (continuous), energy intake (continuous), education level (primary, high school, university), marital status (single, married, divorced, widowed, living with partner), menopausal status at diagnosis (premenopausal, postmenopausal, unknown), body mass index (<20, 20–24.9, 25–29.9, ⩾30 kg m−2), and calendar year of diagnosis (continuous).
  3. cCox proportional hazard model adjusted for the variables above plus disease stage (I, II, III/IV), grade (I, II, III), radiation treatment (yes/no), and chemotherapy and/or hormonal treatment (no chemotherapy or hormonal treatment, hormonal therapy and no chemotherapy, chemotherapy and no hormonal therapy, and hormonal therapy and chemotherapy).
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