Table 3 Interrelationships between different pathological and clinical parameters in patients selected for potentially curative resection for oesophageal adenocarcinoma (n=98)

From: The relationship between tumour necrosis, tumour proliferation, local and systemic inflammation, microvessel density and survival in patients undergoing potentially curative resection of oesophageal adenocarcinoma

 

Sex

mGPS

TNM stage

Tumour differentiation

Resection margin

LNR

Klintrup– Makinen score

Necrosis score

CD8 tertiles

CD68 tertiles

Ki67 tertiles

CD34 tertiles

Neo-adjuvant therapy

Age in years (<65/65–74/75 years)

0.199

0.248

0.688

0.939

0.991

0.586

0.977

0.505

0.510

0.749

0.110

0.923

0.639

Sex (male/female)

 

0.155

0.605

0.008

1.00

0.170

0.302

0.091

0.609

0.203

0.813

0.693

0.400

mGPS

  

0.823

0.616

0.569

0.328

0.894

0.228

0.243

0.838

0.311

0.723

0.988

TNM stage (I/II/III)

   

0.008

<0.001

<0.001

0.403

0.754

0.203

0.593

0.430

0.081

0.420

Tumour differentiation (well-mod/poor)

    

1.00

<0.001

0.322

0.012

0.422

0.024

0.655

0.922

0.838

Resection margin (R0/R1)

     

0.004

0.144

0.344

0.004

0.362

0.307

0.719

0.242

LNR

      

0.009

0.388

0.093

0.332

0.293

0.168

0.417

Klintrup–Makinen score (low/igh grade)

       

1.00

0.002

0.078

0.105

0.813

1.00

Necrosis score (low/high grade)

        

0.219

0.724

0.140

0.109

0.839

CD8 tertiles

         

0.002

0.051

0.044

0.016

CD68 tertiles

          

<0.001

0.994

0.004

Ki67 tertiles

           

0.050

<0.001

CD34

            

0.261

  1. Abbreviations: LNR=lymph node ratio; mGPS=modified Glasgow Prognostic score; TNM=tumour node metastasis.