Table 4 Interrelationships between different pathological and clinical parameters in patients selected for potentially curative resection for oesophageal adenocarcinoma without neo-adjuvant therapy (n=53)

	Sex	mGPS	TNM stage	Tumour differentiation	Resection margin	LNR	Klintrup– Makinen score	Necrosis score	CD8 tertiles	CD68 tertiles	Ki67 tertiles	CD34 tertiles
Age in years (<65/65–74/⩾75 years)	0.131	0.262	0.706	0.978	0.674	0.412	0.991	0.266	0.951	0.753	0.375	0.952
Sex (male/female)		0.545	0.654	0.070	0.706	0.259	0.416	0.302	0.615	0.580	0.433	0.726
mGPS			0.624	0.645	0.988	0.085	0.697	0.833	0.661	0.440	0.454	0.806
TNM stage (I/II/III)				0.034	0.001	<0.001	0.325	0.380	0.169	0.229	0.503	0.183
Tumour differentiation (well-mod/poor)					1.00	0.001	0.503	0.053	0.906	0.028	0.740	0.849
Resection margin (R0/R1)						0.011	0.149	0.074	0.032	0.347	0.789	0.726
LNR							0.008	0.921	0.042	0.076	0.198	0.318
Klintrup–Makinen score (low/high grade)								0.509	0.011	0.722	0.160	0.412
Necrosis score (low/high grade)									0.485	0.359	0.051	0.685
CD8 tertiles										0.083	0.570	0.799
CD68 tertiles											0.259	0.709
Ki67 tertiles												0.507

Abbreviations: LNR=lymph node ratio; mGPS=modified Glasgow Prognostic score; TNM=tumour node metastasis.

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