Table 3 Interrelationships between clinicopathological characteristics of patients and protein expression/activation with renal cancer

From: Expression and prognostic significance of Src family members in renal clear cell carcinoma

 

Univariate analysis

Multivariate analysis

 

Numbers

P -value

P -value

HR

Age (<60/>60)

29/28

0.201

  

T stage (T1/T2/T3/T4)

26/12/17/2

0.001

0.001

2.35 (1.41–3.91)

Grade (1/2/3/4)

10/26/15/6

0.012

  

Tumour necrosis (absence/presence)

32/25

0.092

  

c-Src nuc (negative/positive)

31/26

0.437

  

c-Src cyto (negative/positive)

32/25

0.95

  

c-Src mem (negative/positive)

29/28

0.097

  

Y527 Src nuc (negative/positive)

34/23

0.72

  

Y527 Src cyto (negative/positive)

31/26

0.968

  

Y527 Src mem (negative/positive)

29/28

0.329

  

Y416 Src nuc (negative/positive)

29/28

0.799

  

Y416 Src cyto (negative/positive)

32/25

0.311

  

Y416 Src mem (negative/positive)

29/28

0.79

  

Y861 Fak nuc (negative/positive)

29/28

0.489

  

Y861 Fak cyto (negative/positive)

36/21

0.001

0.006

3.35 (1.40–7.98)

Y861 Fak mem (negative/positive)

30/27

0.678

  
  1. Abbreviation: HR=hazard ratio.
  2. Figures in bold denote significant P-values.