Table 3 Interrelationships between clinicopathological characteristics of patients and protein expression/activation with renal cancer
From: Expression and prognostic significance of Src family members in renal clear cell carcinoma
Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|
Numbers | P -value | P -value | HR | |
Age (<60/>60) | 29/28 | 0.201 | ||
T stage (T1/T2/T3/T4) | 26/12/17/2 | 0.001 | 0.001 | 2.35 (1.41–3.91) |
Grade (1/2/3/4) | 10/26/15/6 | 0.012 | ||
Tumour necrosis (absence/presence) | 32/25 | 0.092 | ||
c-Src nuc (negative/positive) | 31/26 | 0.437 | ||
c-Src cyto (negative/positive) | 32/25 | 0.95 | ||
c-Src mem (negative/positive) | 29/28 | 0.097 | ||
Y527 Src nuc (negative/positive) | 34/23 | 0.72 | ||
Y527 Src cyto (negative/positive) | 31/26 | 0.968 | ||
Y527 Src mem (negative/positive) | 29/28 | 0.329 | ||
Y416 Src nuc (negative/positive) | 29/28 | 0.799 | ||
Y416 Src cyto (negative/positive) | 32/25 | 0.311 | ||
Y416 Src mem (negative/positive) | 29/28 | 0.79 | ||
Y861 Fak nuc (negative/positive) | 29/28 | 0.489 | ||
Y861 Fak cyto (negative/positive) | 36/21 | 0.001 | 0.006 | 3.35 (1.40–7.98) |
Y861 Fak mem (negative/positive) | 30/27 | 0.678 |