Table 1 Clinico-pathological details of each of the case–control series analysed

From: The TERT variant rs2736100 is associated with colorectal cancer risk

   

rs2736100 genotype

   

Cases

Controls

Study

Cases

Controls

GG

GT

TT

RAF

GG

GT

TT

RAF

AUS

376 (379)

1702 (1703)

79

190

107

0.54

445

860

397

0.49

CFR1

1175 (1175)

999 (999)

271

576

328

0.52

261

504

234

0.49

CFR2

796 (796)

2232 (2234)

181

415

200

0.51

584

1102

546

0.49

LP1

890 (890)

900 (900)

207

442

241

0.52

237

427

236

0.50

SP1

962 (973)

998 (998)

218

498

246

0.52

261

469

268

0.50

VQ

1793 (1794)

2681 (2686)

450

897

446

0.50

743

1274

664

0.49

Replication

10 047 (10 488)

6918 (7137)

2337

5087

2623

0.51

1727

3446

1745

0.50

  1. Abbreviations: AUS=Australian; CFR=Colon Cancer Family Registry; LP1=London 1; RAF=risk allele frequency (rs2736100-T); VQ=VQ58.
  2. Numbers in brackets indicate post-QC sample individuals, whereas numbers not in brackets indicate post-QC sample individuals with rs2736100 genotypes.