Table 5 Risk of death from lung cancer by cumulative silica dust exposure in mg m−3-years by categories after exclusion of known silicotics, 1946–2003

From: Quantitative relationship between silica exposure and lung cancer mortality in German uranium miners, 1946–2003

Cohort excluding known silicotics

‘Known’ silicotics

Silica dust in mg m − 3 -years

Person-years

# of lung cancer deaths

RR 95%CI adjusted for radon and arsenic

RR 95%CI adjusted for radon and arsenic with effect modifiers

Person-years

# of lung cancer deaths

0–0.5

665 199

137

1.00 Reference

1.00 Reference

16 497

0

0.5–2

390 539

276

1.12 (0.86–1.31)

0.98 (0.79–1.18)

4019

7

2–5

267 161

333

1.12 (0.88–1.36)

0.97 (0.78–1.17)

7361

23

5–10

223 766

379

1.06 (0.82–1.30)

0.88 (0.69–1.07)

14 146

51

10–20

219 248

675

1.44 (1.10–1.78)

1.16 (0.89–1.43)

44 600

261

20–30

66 313

308

1.64 (1.13–2.15)

1.31 (0.92–1.70)

41 874

356

30–56

11 864

68

1.87 (0.98–2.77)

1.31 (0.63–1.99)

11 192

121

Total

1 844 090

2176

  

139 692

819

  1. Abbreviations: CI=confidence interval; RR=relative risk.
  2. RR adjusted for radon and arsenic (forth column) and for radon with exponential inclusion of the effect modifiers age at median exposure, time since median exposure and radon exposure rate and arsenic (fifth column) as continuous variables in an additive way
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